Swelling or edema represents a typical indication of severe liver disease progression. Fluid accumulation in tissues becomes more noticeable in the feet and hands, because the liver fails to function correctly. The liver’s inability to produce sufficient albumin proteins causes blood vessels to swell with fluid. Fluid leakages into tissues occur because of absent proteins, which results in swelling and discomfort. The swelling of hands and feet serves as an indication of liver disease worsening, while it commonly appears together with weight gain, abdominal swelling and fatigue.
Sources
American Liver Foundation: Signs of Liver Disease
Cleveland Clinic: Palmar Erythema and Liver Disease
National Institute of Diabetes and Digestive and Kidney Diseases: Liver Disease Overview
MedlinePlus: Jaundice and Liver Health
Disclaimer: This article is informational only and not a substitute for medical advice