Some individuals are born with structural abnormalities or inherited disorders of the kidneys. Examples include polycystic kidney disease, Alport syndrome, and congenital obstructions. Since the kidneys may be malformed or genetically predisposed to weaken, leakage of proteins can appear early in life.
These conditions can also have an impact on the pattern of urine flow or on mineral processing. Poor drainage, repeated infections, or unusual tissue growths can provide ideal conditions for kidney stones to form. Individuals with congenital kidney disorders usually need to be monitored throughout their lives. Early diagnosis of proteinuria and early passage of stones can often avert more serious complications later.
Chronic renal infections, Recurrent urinary tract infections or chronic inflammation in the kidneys can progressively weaken tissues over time. With progression, this becomes a less effective filtration system that starts to allow protein to escape into the urine. Chronic infections are also known to encourage stone formation as they change the pH of urine, increase bacterial buildup, and create debris that acts as a seed for stone growth. One kind of stone, called a struvite stone, can form in response to an infection. These stones can grow quite large and may fill the renal pelvis, taking the shape of it. Therefore, quick treatment and prevention of recurrence of infection is important in kidney function protection.
